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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NDC80
All Species:
19.39
Human Site:
S66
Identified Species:
32.82
UniProt:
O14777
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14777
NP_006092.1
642
73913
S66
K
R
T
S
G
H
G
S
R
N
S
Q
L
G
I
Chimpanzee
Pan troglodytes
XP_512046
642
73980
S66
K
R
T
S
G
H
G
S
R
N
S
Q
L
G
I
Rhesus Macaque
Macaca mulatta
XP_001086615
642
73921
S66
K
R
T
S
G
H
G
S
R
N
S
Q
L
G
I
Dog
Lupus familis
XP_537313
642
73907
S66
K
R
T
S
G
H
G
S
R
N
S
Q
F
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0F1
642
73943
S66
K
R
T
S
G
H
G
S
R
N
S
Q
L
G
I
Rat
Rattus norvegicus
NP_001119742
329
38011
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505423
649
75199
G66
F
F
G
K
R
T
S
G
P
G
S
R
N
S
Q
Chicken
Gallus gallus
Q76I89
640
73723
G66
F
F
G
K
R
A
S
G
A
G
G
S
R
N
S
Frog
Xenopus laevis
Q8AWF5
638
74459
R66
R
A
S
N
G
T
A
R
T
S
Q
Y
G
A
F
Zebra Danio
Brachydanio rerio
Q6DRJ7
632
73198
M68
A
G
G
Q
R
N
S
M
F
G
S
Y
G
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17635
590
68894
K66
S
V
A
P
R
D
V
K
S
L
V
S
L
N
G
Sea Urchin
Strong. purpuratus
XP_001197919
631
72734
N71
K
S
T
F
G
F
S
N
T
R
R
P
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40460
691
80469
S97
S
N
S
R
N
S
V
S
R
L
S
I
N
Q
L
Red Bread Mold
Neurospora crassa
Q96U60
743
84837
P104
T
P
G
S
S
G
I
P
R
S
S
Q
E
L
D
Conservation
Percent
Protein Identity:
100
99.6
99.2
92.5
N.A.
83.9
44.5
N.A.
75.5
71.3
56.8
44.2
N.A.
N.A.
N.A.
21.8
28
Protein Similarity:
100
99.6
99.5
97.1
N.A.
91.5
47.9
N.A.
87.9
84.7
77.4
63.8
N.A.
N.A.
N.A.
44.8
51.2
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
6.6
0
6.6
13.3
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
0
N.A.
13.3
0
33.3
20
N.A.
N.A.
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
44.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
8
8
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
15
15
0
8
0
8
0
0
8
0
0
0
8
0
8
% F
% Gly:
0
8
29
0
50
8
36
15
0
22
8
0
15
43
15
% G
% His:
0
0
0
0
0
36
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
36
% I
% Lys:
43
0
0
15
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
15
0
0
36
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
8
0
8
0
36
0
0
15
15
0
% N
% Pro:
0
8
0
8
0
0
0
8
8
0
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
8
43
0
8
8
% Q
% Arg:
8
36
0
8
29
0
0
8
50
8
8
8
8
0
0
% R
% Ser:
15
8
15
43
8
8
29
43
8
15
65
15
8
15
15
% S
% Thr:
8
0
43
0
0
15
0
0
15
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
15
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _